KPV is the tripeptide Lys-Pro-Val, the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH).

What is KPV studied for?

KPV is studied for anti-inflammatory activity, including models of inflammatory bowel disease and skin inflammation. Unlike full alpha-MSH, it does not affect pigmentation.

Every batch goes to an independent lab. The current batch was tested across three vials for purity (RP-HPLC), identity (LC-MS), net peptide content, endotoxins, heavy metals and sterility. Each batch's certificate of analysis is published on the lab results page.

How should KPV be stored?

Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?

How much KPV is in a vial?

KPV comes as a white lyophilized powder in a 10mg vial.

Is KPV for human use?

No. KPV is sold for laboratory research use only.

10mg · 99%+ Purity

KPV

KPV is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH), consisting of Lys-Pro-Val.

$52.00

COA Tested 99%+ Purity Research Grade

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99.531% purity View COA

Certificate of Analysis

KPV 10mg · 3 vials tested by an independent lab · RP-HPLC / LC-MS

Batch 2026-KV312

Latest

99.531%

Average purity

Labeled content: 10mg
Net content: 10.78mg (+8%)
Vials tested: 3
Endotoxins: Pass
Heavy metals: Pass
Microbial sterility: Pass
Method: RP-HPLC / LC-MS
Tested: Jul 16, 2026

View full COA

Batch KV298

99.61%

Average purity

Labeled content: 10mg
Net content: 11.65mg (+17%)
Vials tested: 1
Endotoxins: Not Tested
Method: HPLC-UV
Tested: Aug 5, 2025

View full COA

Compound Information

Chemical and structural properties

What it is

What is KPV?

KPV is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH), consisting of Lys-Pro-Val.

Class: Tripeptide (alpha-MSH fragment)
Also known as: Lys-Pro-Val, alpha-MSH (11-13)
Form: White lyophilized powder
Use: Research use only

Molecular profile

Compound Structure

CAS number: 67727-97-3
Molecular formula: C16H30N4O4
Molecular weight: 342.43 g/mol
Amino acids: 3
Sequence: Lys-Pro-Val

PubChem · CID 125672

Storage

Storage & Stability

Store cold
Protect from light
Keep dry

Lyophilized (powder) 2–8°C (36–46°F) Refrigerate · −20°C for long-term storage

Reconstituted 2–8°C (36–46°F) Refrigerate · use within 28 days

Solubility: Soluble in bacteriostatic water

KPV Overview

The three-amino-acid tail of alpha-MSH, studied for anti-inflammatory activity.

Technical overview

KPV (Lys-Pro-Val) is the C-terminal end of alpha-melanocyte-stimulating hormone, positions 11 to 13. It keeps much of the hormone's anti-inflammatory activity but none of its effect on pigmentation, and research suggests it enters cells through the PepT1 transporter.

Research applications

KPV is studied in models of inflammatory bowel disease, skin inflammation and wound healing, including its effects on NF-κB signalling and inflammatory cytokines.

FAQs

What is KPV?

KPV is the tripeptide Lys-Pro-Val, the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH).
What is KPV studied for?

KPV is studied for anti-inflammatory activity, including models of inflammatory bowel disease and skin inflammation. Unlike full alpha-MSH, it does not affect pigmentation.
How is KPV tested?

Every batch goes to an independent lab. The current batch was tested across three vials for purity (RP-HPLC), identity (LC-MS), net peptide content, endotoxins, heavy metals and sterility. Each batch's certificate of analysis is published on the lab results page.
How should KPV be stored?

Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?
How much KPV is in a vial?

KPV comes as a white lyophilized powder in a 10mg vial.
Is KPV for human use?

No. KPV is sold for laboratory research use only.