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10mg · 99%+ Purity

MELANOTAN I

Melanotan I (Melanotan 1, MT-1), also known as afamelanotide, is a synthetic alpha-MSH analogue containing Nle4 and D-Phe7 modifications.

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99.576% purity View COA

Certificate of Analysis

Melanotan 1 10mg · 3 vials tested by an independent lab · RP-HPLC / LC-MS

Certificate of Analysis

Compound Information

Chemical and structural properties

What it is

What is Melanotan 1?

Melanotan I (Melanotan 1, MT-1), also known as afamelanotide, is a synthetic alpha-MSH analogue containing Nle4 and D-Phe7 modifications.

Class
Alpha-MSH analogue (MC1R agonist)
Also known as
MT-1, afamelanotide
Form
White lyophilized powder
Use
Research use only

Molecular profile

Compound Structure

CAS number
75921-69-6
Molecular formula
C78H111N21O19
Molecular weight
1646.8 g/mol
Amino acids
13
Sequence
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
PubChem · CID 16197727

Storage

Storage & Stability

  • Store cold
  • Protect from light
  • Keep dry
Lyophilized (powder) 2–8°C (36–46°F) Refrigerate · −20°C for long-term storage
Reconstituted 2–8°C (36–46°F) Refrigerate · use within 28 days

Melanotan 1 Overview

A long-lasting version of the body's own tanning hormone, alpha-MSH.

Technical overview

Melanotan 1 is a 13-amino-acid linear peptide with the same sequence as alpha-MSH except for two substitutions: norleucine at position 4 and D-phenylalanine at position 7. Those changes make it far more resistant to breakdown and more potent at the melanocortin-1 receptor (MC1R).

Research applications

Melanotan 1 is studied in research on melanogenesis (skin pigmentation), protection from UV light, and MC1R signalling in melanocytes.

FAQs

  • What is Melanotan 1?

    Melanotan 1 (MT-1, afamelanotide) is a synthetic 13-amino-acid analogue of alpha-MSH. Two substitutions, Nle4 and D-Phe7, make it far more stable than the natural hormone.

  • What is Melanotan 1 studied for?

    It is studied in melanocortin-1 receptor (MC1R) research, including skin pigmentation (melanogenesis) and protection from UV light.

  • What is the difference between Melanotan 1 and Melanotan 2?

    Melanotan 1 is a linear peptide that acts mainly on MC1R. Melanotan 2 is a smaller cyclic peptide that acts on several melanocortin receptors, so it is also studied in appetite and sexual-function research.

  • How is Melanotan 1 tested?

    Every batch goes to an independent lab. The current batch was tested across three vials for purity (RP-HPLC), identity (LC-MS), net peptide content, endotoxins, heavy metals and sterility. Each batch's certificate of analysis is published on the lab results page.

  • How should Melanotan 1 be stored?

    Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?

  • How much Melanotan 1 is in a vial?

    Melanotan 1 comes as a white lyophilized powder in a 10mg vial.

  • Is Melanotan 1 for human use?

    No. Melanotan 1 is sold for laboratory research use only.

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