TB-500 is a synthetic seven-amino-acid peptide, Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, copied from the actin-binding region of thymosin beta-4, a protein found in nearly every human cell.

Is TB-500 the same as thymosin beta-4?

No. Thymosin beta-4 is the full 43-amino-acid protein. TB-500 is a synthetic copy of positions 17 to 23, the part that binds actin, which is why the two are studied and discussed together.

Is there a BPC-157 and TB-500 blend?

Yes. The Wolverine peptide combines 10mg of BPC-157 and 10mg of TB-500 in one vial.

How should TB-500 be stored?

Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?

How much TB-500 is in a vial?

TB-500 comes as a white lyophilized powder in a 10mg vial.

Where can I read more about TB-500?

Our guide Wolverine Stack Dosage Guide covers it in depth. To work out how much water to add to a vial, use our peptide reconstitution calculator.

Is TB-500 for human use?

No. TB-500 is sold for laboratory research use only.

10mg · 99%+ Purity

TB-500

TB-500 is a synthetic seven-amino-acid peptide (Ac-LKKTETQ) copied from the actin-binding region of thymosin beta-4, studied in tissue-repair research.

$66.00

COA Tested 99%+ Purity Research Grade

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99.678% purity View COA

Certificate of Analysis

TB-500 10mg · 3 vials tested by an independent lab · RP-HPLC / LC-MS

Batch 2026-TB209

Latest

99.678%

Average purity

Labeled content: 10mg
Net content: 10.44mg (+4%)
Vials tested: 3
Endotoxins: Pass
Heavy metals: Negative
Microbial sterility: No Growth
Method: RP-HPLC / LC-MS
Tested: Jul 16, 2026

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Compound Information

Chemical and structural properties

What it is

What is TB-500?

TB-500 is a synthetic seven-amino-acid peptide (Ac-LKKTETQ) copied from the actin-binding region of thymosin beta-4, studied in tissue-repair research.

Class: Synthetic thymosin beta-4 fragment
Also known as: Thymosin beta-4 (17-23), Ac-LKKTETQ
Form: White lyophilized powder
Use: Research use only

Molecular profile

Compound Structure

CAS number: 885340-08-9
Molecular formula: C38H68N10O14
Molecular weight: 889.0 g/mol
Amino acids: 7
Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH

PubChem · CID 62707662

Storage

Storage & Stability

Store cold
Protect from light
Keep dry

Lyophilized (powder) 2–8°C (36–46°F) Refrigerate · −20°C for long-term storage

Reconstituted 2–8°C (36–46°F) Refrigerate · use within 28 days

Solubility: Soluble in bacteriostatic water

TB-500 Overview

The actin-binding core of thymosin beta-4, made as a short synthetic peptide for tissue-repair research.

Technical overview

TB-500 is the seven-amino-acid sequence Leu-Lys-Lys-Thr-Glu-Thr-Gln, acetylated at its N-terminus, copied from positions 17 to 23 of thymosin beta-4. That stretch holds LKKTET, the motif thymosin beta-4 uses to bind G-actin, the building block of the cell's actin skeleton.

Research applications

Research uses TB-500 to study cell migration, wound closure, blood-vessel growth, and repair of muscle, tendon and skin in animal and cell models, and to separate what the actin-binding region does from the rest of thymosin beta-4.

FAQs

What is TB-500?

TB-500 is a synthetic seven-amino-acid peptide, Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, copied from the actin-binding region of thymosin beta-4, a protein found in nearly every human cell.
Is TB-500 the same as thymosin beta-4?

No. Thymosin beta-4 is the full 43-amino-acid protein. TB-500 is a synthetic copy of positions 17 to 23, the part that binds actin, which is why the two are studied and discussed together.
What is TB-500 studied for?

TB-500 is studied in tissue-repair research, including cell migration, wound closure, blood-vessel growth and muscle and tendon repair in animal and cell models.
Is there a BPC-157 and TB-500 blend?

Yes. The Wolverine peptide combines 10mg of BPC-157 and 10mg of TB-500 in one vial.
How should TB-500 be stored?

Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?
How much TB-500 is in a vial?

TB-500 comes as a white lyophilized powder in a 10mg vial.
Where can I read more about TB-500?

Our guide Wolverine Stack Dosage Guide covers it in depth. To work out how much water to add to a vial, use our peptide reconstitution calculator.
Is TB-500 for human use?

No. TB-500 is sold for laboratory research use only.