10mg · 99%+ Purity
SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide that binds cardiolipin in the inner mitochondrial membrane, studied in mitochondrial research.
Chemical and structural properties
What it is
SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide that binds cardiolipin in the inner mitochondrial membrane, studied in mitochondrial research.
Molecular profile
Storage
A four-amino-acid peptide that goes straight to the inner membrane of the mitochondria.
SS-31 (D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2′,6′-dimethyltyrosine) is one of the Szeto-Schiller peptides developed by Hazel Szeto and Peter Schiller. Its alternating aromatic and basic residues let it cross cell membranes and concentrate in the inner mitochondrial membrane, where it binds cardiolipin, the lipid that holds the electron transport chain together.
SS-31 is studied in mitochondrial research, including cardiolipin stability, electron transport efficiency, reactive oxygen species, and models of heart failure, kidney injury, aging muscle and inherited mitochondrial disease.
SS-31 is a synthetic tetrapeptide, D-Arg-Dmt-Lys-Phe-NH2, that concentrates in the inner mitochondrial membrane and binds cardiolipin.
Yes. Elamipretide is the drug-development name for SS-31, which has also been coded MTP-131 and Bendavia.
SS-31 is studied in mitochondrial research, including electron transport efficiency, reactive oxygen species and models of heart, kidney and muscle aging.
Both are studied in mitochondrial research. SS-31 is a synthetic tetrapeptide that binds cardiolipin inside the mitochondria. MOTS-c is a 16-amino-acid peptide the mitochondria make themselves, studied mainly for its effects on metabolism.
Keep the sealed vial in the refrigerator at 36–46°F (2–8°C), dry and away from light. As a freeze-dried powder it tolerates room temperature for weeks, which is why it ships without ice. Once reconstituted, keep it refrigerated between uses. More in our guide, Do peptides need to be refrigerated?
SS-31 comes as a white lyophilized powder in a 10mg vial.
No. SS-31 is sold for laboratory research use only.
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